Antigen Retrieval Solution (Alkaline)

$300.00

In the process of immunohistochemistry, formalin or paraformaldehyde solution is commonly used to fix the sample material, and the aldehyde group of formaldehyde in the fixative undergoes cross-linking reaction with the protein, which masks the epitope on the surface of the antigen to varying degrees, affecting its binding to the antibody. This antigen retrieval buffer can balance the pH of the solution, dissociate and break the formaldehyde and aldehyde bonds cross-linked with proteins, restore protein molecules, and enhance the binding of antibodies and antigens. At the same time, the surfactant in this antigen retrieval buffer can destroy the surface tension of the liquid and enhance the fluidity of the liquid in the system.

Category: SKU: 4980211

Product will arrive in 2-3 weeks

Principle of Procedure

In the process of immunohistochemistry, formalin or paraformaldehyde solution is commonly used to fix the sample material, and the aldehyde group of formaldehyde in the fixative undergoes cross-linking reaction with the protein, which masks the epitope on the surface of the antigen to varying degrees, affecting its binding to the antibody. This antigen retrieval buffer can balance the pH of the solution, dissociate and break the formaldehyde and aldehyde bonds cross-linked with proteins, restore protein molecules, and enhance the binding of antibodies and antigens. At the same time, the surfactant in this antigen retrieval buffer can destroy the surface tension of the liquid and enhance the fluidity of the liquid in the system.

Size

1L/bottle

 

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